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Monique L den Boer Selected Research

Aspartate-Ammonia Ligase (Asparagine Synthetase)

7/2009Functional analysis of a novel DNA polymorphism of a tandem repeated sequence in the asparagine synthetase gene in acute lymphoblastic leukemia cells.
6/2006Up-regulation of asparagine synthetase expression is not linked to the clinical response L-asparaginase in pediatric acute lymphoblastic leukemia.
6/2005Asparagine synthetase expression is linked with L-asparaginase resistance in TEL-AML1-negative but not TEL-AML1-positive pediatric acute lymphoblastic leukemia.

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Monique L den Boer Research Topics

Disease

34Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
01/2021 - 02/2003
10Neoplasms (Cancer)
12/2019 - 11/2005
9Leukemia
11/2021 - 08/2004
7Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
12/2019 - 09/2005
7Glucocorticoid Receptor Deficiency
06/2015 - 08/2005
5Brain Neoplasms (Brain Tumor)
12/2008 - 08/2006
4Residual Neoplasm
01/2021 - 01/2019
4Ependymoma
12/2008 - 06/2007
3Medulloblastoma
12/2008 - 08/2008
3Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL)
09/2006 - 01/2006
1Hepatic Veno-Occlusive Disease (Disease, Hepatic Veno-Occlusive)
01/2021
1B-Cell Leukemia (Leukemia, B Cell)
01/2017
1Vomiting
07/2013
1Nausea
07/2013
1Philadelphia Chromosome
07/2013
1BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
07/2013
1Headache (Headaches)
07/2013
1Diarrhea
07/2013
1Genetic Translocation (Chromosomal Translocation)
03/2010
1Neoplasm Metastasis (Metastasis)
10/2008
1Primitive Neuroectodermal Tumors (PNET)
06/2007

Drug/Important Bio-Agent (IBA)

10Proteins (Proteins, Gene)FDA Link
01/2019 - 09/2005
9Pharmaceutical PreparationsIBA
07/2013 - 08/2004
8Prednisolone (Predate)FDA LinkGeneric
11/2019 - 08/2004
7Asparaginase (Elspar)FDA Link
11/2019 - 04/2003
7GlucocorticoidsIBA
06/2015 - 08/2005
6Messenger RNA (mRNA)IBA
09/2010 - 02/2003
4Glucocorticoid Receptors (Glucocorticoid Receptor)IBA
06/2015 - 08/2005
3Transcription Factors (Transcription Factor)IBA
11/2021 - 01/2017
3Vincristine (Oncovin)FDA LinkGeneric
11/2019 - 08/2004
3Aspartate-Ammonia Ligase (Asparagine Synthetase)IBA
07/2009 - 06/2005
2Imatinib Mesylate (Gleevec)FDA Link
03/2014 - 07/2013
2Biological ProductsIBA
12/2008 - 05/2007
2Tumor Biomarkers (Tumor Markers)IBA
10/2008 - 06/2007
2Cytarabine (Cytosar-U)FDA LinkGeneric
01/2006 - 02/2003
1T-Cell Antigen Receptors (T-Cell Receptor)IBA
01/2021
1Immunoconjugates (Immunoconjugate)IBA
01/2021
1Prednisone (Sone)FDA LinkGeneric
01/2021
1Immunoglobulins (Immunoglobulin)IBA
01/2021
1Inotuzumab OzogamicinIBA
01/2021
1Fibroblast Growth Factors (Fibroblast Growth Factor)IBA
12/2019
1Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA
12/2019
1Codon (Codons)IBA
12/2019
1Hydroxychloroquine (Plaquenil)FDA LinkGeneric
01/2019
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
01/2017
1Oncogene Proteins (Oncogene Protein)IBA
01/2017
1InflammasomesIBA
06/2015
1Caspase 1 (ICE Protease)IBA
06/2015
1Hydrocortisone (Cortisol)FDA LinkGeneric
04/2015
1Tyrosine Kinase InhibitorsIBA
03/2014
1Dasatinib (BMS 354825)FDA Link
07/2013
1MicroRNAs (MicroRNA)IBA
03/2010
1DNA (Deoxyribonucleic Acid)IBA
07/2009
1Amino AcidsFDA Link
10/2008
1Death Domain ReceptorsIBA
08/2008
1Insulin-Like Growth Factor Binding Protein 2IBA
08/2008
1Insulin-Like Growth Factor II (Somatomedin A)IBA
08/2008
1Insulin-Like PeptidesIBA
08/2008
1Somatomedin Receptors (Somatomedin Receptor)IBA
08/2008
1Insulin-Like Growth Factor Binding Protein 5IBA
08/2008
1Insulin-Like Growth Factor Binding ProteinsIBA
08/2008
1Insulin-Like Growth Factor Binding Protein 3IBA
08/2008
1Annexin A1IBA
06/2007
1ProteomeIBA
06/2007
1Drug CombinationsIBA
06/2007
1Biomarkers (Surrogate Marker)IBA
06/2007
1StathminIBA
06/2007
1Sirolimus (Rapamycin)FDA Link
10/2006
1AlbuminsIBA
08/2006
1Apolipoprotein A-II (Apolipoprotein A2)IBA
08/2006
1Member 1 Subfamily B ATP Binding Cassette TransporterIBA
06/2006
1CladribineFDA LinkGeneric
01/2006
1fludarabineIBA
01/2006
1Histone Deacetylases (Histone Deacetylase)IBA
12/2005
1Co-Repressor ProteinsIBA
12/2005
1Histone Deacetylase InhibitorsIBA
12/2005
1DepsipeptidesIBA
12/2005
1Neoplasm Antigens (Tumor Antigens)IBA
11/2005
1AntigensIBA
11/2005
1EpitopesIBA
11/2005
1Peptides (Polypeptides)IBA
11/2005
1Adenosine Diphosphate (ADP)IBA
09/2005
1Adenosine Diphosphate Ribose (ADP-Ribose)IBA
09/2005
1Caspase 2IBA
09/2005
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
09/2005
1Protein Isoforms (Isoforms)IBA
09/2005
1Daunorubicin (Cerubidine)FDA LinkGeneric
08/2004
1EnzymesIBA
02/2003

Therapy/Procedure

12Therapeutics
01/2021 - 09/2006
5Drug Therapy (Chemotherapy)
01/2021 - 08/2004
1Stem Cell Transplantation
01/2021
1Investigational Therapies (Experimental Therapy)
07/2013
1Radiotherapy
12/2008
1Lasers (Laser)
08/2006
1Immunotherapy
11/2005
1Combination Drug Therapy (Combination Chemotherapy)
04/2005